With Shopify Markets, you can collect duties and import taxes from your international customers at checkout. If your store is not eligible, or you don’t want to use this functionality, you can use a third party app to estimate duty and import taxes at checkout. 

With Shopify’s tax engine, you can set up tax rates on products and shipping based on your business’s location, or the location you’re shipping to. Learn more about setting up your taxes here, and consult a tax advisor if you’re uncertain about your requirements. In the majority of cases, Shopify’s tax engine will allow you to implement your tax requirements. If your desired customer experience or internal reporting is not supported by Shopify’s tax engine on a single store, you may consider opening additional stores to sell in the countries where you have unique tax requirements. 

With Shopify, you can set up shipping profiles, consisting of different shipping zones and rates, that you can associate to your products. Typically, you will be able to accurately set shipping rates for all your international markets from a single store. Learn more about setting up your shipping here.